04 Jul Poly(ethylene glycol), α-hydroxy, ω-phosphonic acid
Product of the month | July 2023
SP-1P-1-006 is a polyethylene glycol (PEG) bearing two different end groups: i) a phosphonic acid group known for its adhesion properties, and ii) a hydroxyl group. This heterobifunctional polymer is highly soluble in water and biocompatible.
Thanks to the phosphonic acid terminal function, this polyether can be grafted on metallic surfaces such as alumina[1], iron or cerium oxide nanoparticles[2,3] leading to interesting stability properties in water and in cell culture media.
In terms of applications, this polymer is described in the development of hydrophilic organically-modified ceramic membranes for wastewater treatment[1], polyurethane lacquer[2] and can be used for several biomedical applications, in particular by the functionalization of Cerium Oxide nanoparticles.[3]
SP-1P-1-006 is an oligomer with 8 to 11 units of PEG with a molecular weight around 500-650g/mol.
References
[1] N. Kyriakou et al.,Hydrolytic stability of PEG-grafted γ-alumina membranes: Alkoxysilane vs phosphonic acid linking groups: Microporous and Mesoporous Materials, (2020), 307, 110516 >
[2] A. Saadat-Monfared, Polyurethane nanocomposite films containing nano-cerium oxide as UV absorber. Part 1. Static and dynamic light scattering, small angle neutron scattering and optical studies: Colloids and Surfaces, A: Physicochemical and Engineering Aspects (2012), 408, 64-70 >
[3] L. Qi, Interfacial Activity of Phosphonated-PEG Functionalized Cerium Oxide Nanoparticles: Langmuir (2012), 28(31), 11448-11456 >
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