SEC
Size exclusion chromatography (SEC) or gel permeation chromatography (GPC) is a common method for determining the average and relative molecular weights and the molecular weight distribution of polymers.
This technique is widely used within the company: to (i) characterize the molecular weights of polymers (Mn, Mw, polydispersity index), (ii) identify the distribution of oligomers, (iii) control the kinetics of polymerization reactions or (iv) study the stability of synthesized polymers (ageing). It can also be used to highlight the evolution of molecular weight that is sometimes observed during the synthesis of various resins. Depending on the polymer solubility, we can perform SEC chromatography either in DMF or THF. Our classical standards: PMMA, PS.
Equipment | Agilent 1260 Infinity with RI (refractive index) detection
Solvent: THF, Agilent Polypore (200 to 2000000 Da) columns – calibrants: PS and PMMA
Solvent: DMF, PolarGel M (1000 to 500000 Da) columns – calibrants: PMMA and PEG