SEC
Size exclusion chromatography (SEC) or gel permeation chromatography (GPC) is a common method for determining the average and relative molecular weights as well as the molecular weight distribution of polymers.
This technique is widely used within the company: to (i) characterize the molecular weights of polymers (Mn, Mw, polydispersity index), (ii) identify the distribution of oligomers, (iii) control the kinetics of polymerization reactions or (iv) study the stability of synthesized polymers (aging). Depending on the polymer solubility, the SEC chromatography analysis can be performed under THF or DMF. The relative’s characteristics values are determined by using either PMMA, PEG or PS standards.
Equipment | Agilent 1260 Infinity II with RI (refractive index) detection
Solvent: THF, Columns : Agilent Polypore (200 to 2000000 Da) – Standards: PS and PMMA
Solvent: DMF, Columns : Agilent PolarGel M (1000 to 500000 Da)- Standards: PEG and PMMA